by padra | Jan 31, 2018 | Uncategorized
In a selected group of men with Peyronie’s disease (PD), ESWT appears to be safe, has moderate efficacy and is associated with high patient satisfaction rate in the short term.
Peyronie’s disease and low intensity shock wave therapy: Clinical outcomes and patient satisfaction rate in an open-label single arm prospective study in Australian men
The majority of patients have PD history longer than 6 months (mean, 12.8 months; range, 6-28 months). Two thirds of patients have received and failed oral medical therapy. There were improvements in penile curvature (more than 15 degrees in 33% of men), plaque hardness (60% of men) and penile pain (4 out of 6 men) following LiESWT. There was a moderate improvement in IIEF-5 score (>5 points reported in 20% of men). No complication was reported and the majority of patients were satisfied (rated 4 out of 5; 70% of men) and would recommend this therapy to others.
Shown effective in patient age ≥18 years, failed medical therapy, presence of palpable plaque and/or penile pain, and penile curvature.
Excluded patients were complex curvature (more than 1 axis deviation or curvature >90 degrees), hourglass deformity, 2 or more palpable plaques, previous Peyronie’s surgery (including penile prosthesis implant) and significant ED unresponsive to medical therapy.
by padra | Jan 15, 2018 | ED
“Penile Low Intensity Shock Wave Treatment is Able to Shift PDE5i Nonresponders to Responders: A Double-Blind, Sham Controlled Study”
Noam D. Kitrey
In the low intensity shock wave treatment group and the sham group 54.1% and 0% of patients, respectively, achieved erection hard enough for vaginal penetration, that is an EHS (Erection Hardness Score) of 3 (p <0.0001). According to changes in the IIEF-EF (International Index of Erectile Function-Erectile Function) score treatment was effective in 40.5% of men who received low intensity shock wave treatment but in none in the sham group (p = 0.001). Of patients treated with shock waves after sham treatment 56.3% achieved erection hard enough for penetration (p <0.005).
“Low intensity shock wave treatment is effective even in patients with severe erectile dysfunction who are PDE5i nonresponders. After treatment about half of them were able to achieve erection hard enough for penetration with PDE5i. Longer followup is needed to establish the place of low intensity shock wave treatment in these challenging cases.”
Los Angeles Clinic.
by padra | Jan 15, 2018 | ED
Low-Intensity Extracorporeal Shock Wave Therapy—A Novel Effective Treatment for Erectile Dysfunction in Severe ED Patients Who Respond Poorly to PDE5 Inhibitor Therapyjsm_2498 2
Ilan Gruenwald, MD, Boaz Appel, MD, and Yoram Vardi, MD
Neuro-urology Unit, Rambam Healthcare Campus, Haifa, Israel
Results. “Twenty-nine men (mean age of 61.3) completed the study. Their mean IIEF-ED scores increased from
8.8 1 (baseline) to 12.3 1 at FU1 (P = 0.035). At FU2 (on active PDE5i treatment), their IIEF-ED further
increased to 18.8 1 (P < 0.0001), and 72.4% (P < 0.0001) reached an EHS of 3 (allowing full sexual intercourse).
A significant improvement (P = 0.0001) in penile hemodynamics was detected after treatment and this improvement
significantly correlated with increases in the IIEF-ED (P < 0.05). No noteworthy adverse events were reported.
Conclusions. Penile LI-ESWT is a new modality that has the potential to treat a subgroup of severe ED patients.
These preliminary data need to be reconfirmed by multicenter sham control studies in a larger group of ED patients. ”
Los Angeles Men’s Health Clinic
by padra | Jan 2, 2018 | ED
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