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Low-Intensity Extracorporeal Shock Wave Therapy—A Novel Effective Treatment for Erectile Dysfunction in Severe ED Patients Who Respond Poorly to PDE5 Inhibitor Therapyjsm_2498 2
Ilan Gruenwald, MD, Boaz Appel, MD, and Yoram Vardi, MD
Neuro-urology Unit, Rambam Healthcare Campus, Haifa, Israel
Results. “Twenty-nine men (mean age of 61.3) completed the study. Their mean IIEF-ED scores increased from
8.8 1 (baseline) to 12.3 1 at FU1 (P = 0.035). At FU2 (on active PDE5i treatment), their IIEF-ED further
increased to 18.8 1 (P < 0.0001), and 72.4% (P < 0.0001) reached an EHS of 3 (allowing full sexual intercourse).
A significant improvement (P = 0.0001) in penile hemodynamics was detected after treatment and this improvement
significantly correlated with increases in the IIEF-ED (P < 0.05). No noteworthy adverse events were reported.
Conclusions. Penile LI-ESWT is a new modality that has the potential to treat a subgroup of severe ED patients.
These preliminary data need to be reconfirmed by multicenter sham control studies in a larger group of ED patients. ”
Los Angeles Men’s Health Clinic